Sound Waves & Tremors

A clinical trial testing the effect of sound waves on tremors Focused ultrasound is an emerging approach to treating Parkinson's that uses sound waves rather than surgery or medication to target specific areas of the brain. This trial is testing a non-invasive version called transcranial focused ultrasound, delivered through the skull, to see whether it can safely improve motor symptoms. Participants receive 20 sessions of either active or sham stimulation over 4 to 6 weeks, with follow-up continuing for 3 months. Neither participants nor the researchers measuring outcomes know who received the active treatment, which helps ensure the results reflect the real effect of the stimulation rather than expectation. The study is enrolling 60 adults aged 22 to 80 with confirmed Parkinson's and a motor exam score of 25 or higher when off medication, on stable Parkinson's medications for at least 30 days. People with prior deep brain stimulation or brain surgery, low cognitive scores, a history of seizures, or MRI contraindications are not eligible. See full listing