Effect of long-term Tai Chi training on Parkinson's disease: a 3.5-year follow-up cohort study

Tai Chi has demonstrated beneficial effects on both motor and non-motor symptoms of Parkinson's disease (PD). This study aimed to determine whether long-term Tai Chi training could sustain improvements in PD patients. From January 2016, two cohorts were established: one of PD patients undergoing Tai Chi training (n=143) and a control group of PD patients without exercise (n=187). Assessments were conducted at baseline, November 2019, October 2020, and June 2021. Results showed that Tai Chi training slowed the annual deterioration in motor and non-motor symptoms, delayed the need for increased antiparkinsonian therapies, and led to a significantly lower annual increase in the levodopa equivalent daily dosage. Overall, patients benefited from Tai Chi in terms of improved symptoms and reduced complications. Thus, long-term Tai Chi training offers sustained benefits for PD patients, enhancing both motor and non-motor functions while reducing complications.