
Regular exercise linked to slower neurodegeneration in Parkinson's disease
August 8, 2025
LeahJSA new study published in Neurology suggests that regular physical activity may slow the progression of brain changes linked to early Parkinson’s disease.
What the Study Found
Researchers followed 120 people with early Parkinson’s over four years. Using brain scans (MRI) and physical activity data, they found that those who stayed regularly active showed:
Less thinning in brain areas important for memory and thinking, such as the temporal and parietal lobes
Slower volume loss in the hippocampus and amygdala, which support memory and emotion
Why This Matters
These brain changes were linked to better preservation of memory and attention, suggesting that regular physical activity may help protect cognitive function in people with Parkinson’s—not just reduce physical symptoms.
Key Takeaway
Staying active could do more than improve daily life with Parkinson’s—it might slow how the disease affects the brain over time. As co-author Dr. Pablo Mir put it: "Exercise may not just help with symptoms—it could also impact disease progression."
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