The role of lifestyle interventions in symptom management and disease modification in Parkinson's disease

Summary Emerging evidence indicates that sustainable lifestyle changes—such as increasing physical activity, adopting healthy dietary patterns, and managing stress—can provide symptomatic benefits and potentially slow neurodegeneration in Parkinson's disease. Combining these interventions could produce synergistic effects, addressing multiple aspects of the pathophysiology. Despite the challenges of long-term adherence, innovative approaches such as digital tools and personalised strategies can support sustained lifestyle modifications. Tailoring interventions to individual needs and cultural contexts is crucial, especially in diverse socioeconomic settings. Future research should focus on large-scale, long-term studies to better understand the disease-modifying potential of lifestyle interventions and explore the biological mechanisms underlying their benefits. Overall, integrating lifestyle modifications into routine care offers a promising, accessible avenue to improve quality of life and potentially alter the progression of Parkinson's disease.